Mohammed T. N. QAOUD

Dr. Inst. MOHAMMED T. N. QAOUD

Faculty of Pharmacy

E-mail mqaoud@ciu.edu.tr
Telephone number +90 392 671 11 11
Extension 2658
Office 244
Other information

CURRICULUM VITAE

Education
  • Gazi Üni. Farmasötik Kimya (PhD, 2023)
  • Jordan Uni. of Science & Technology Farmasötik Teknoloji (Master, 2017)
  • Al azar Uni. Eczacılık (Undergraduate, 2011)
Publications

Articles published in peer reviewed international journals (SCI,SSCI,Arts and Humanities)

  • Tripeptide linked dispiro cyclotriphosphazene conjugates: Synthesis, molecular docking analysis of compounds binding within cancer cell line receptors and in vitro cytotoxic and genotoxic activities. Çalışkan, Capan, Qaoud MT et al Bioorganic Chemistry. https://doi.org/10.1016/j.bioorg.2024.107621 - 2024
  • Phosphazene Tripeptide Conjugates: Design, Synthesis, In Vitro Cytotoxicity and Genotoxicity, Molecular Interactions in Binding Pockets on Human Breast and Colon Cancer Cell Lines. Eray,Furkan, İrfan, Suat, Reda, Mohammed T. Qaoud, ChemMedChem. 2024. https://doi.org/10.1002/cmdc.202400570 - 2024
  • Integrative bioinformatic and experimental analysis of benzoylbenzodioxol derivatives: hypoglycemic potential in diabetic mice. Hawash, Jaradat, Abualhasan, Jadallah, Fashafsheh, Zaid, Qamhia, Qneibi, Qaoud MT et al 3 Biotech. 2024 Oct;14(10):1-4. https://doi.org/10.1007/s13205-024-04103-6 - 2024
  • Next-Generation Carbazole-Linked 1, 2, 4-Triazole-Thione Derivatives: Strategic Design, Synthesis, Molecular Docking, and Evaluation of Antidiabetic Potential. IrfanCapan,*MohammedHawash,MohammedT.Qaoud, and Nidal Jaradat. ACS Omega. 2024. https://doi.org/10.1021/acsomega.4c07896 - 2024
  • Synthesis of novel carbazole hydrazine-carbothioamide scaffold as potent antioxidant, anticancer and antimicrobial agents. İrfan Çapan, Mohammed Hawash, Mohammed T. Qaoud et al BMC chemistry. 2024 May 21;18(1):102. https://doi.org/10.1186/s13065-024-01207-1 - 2024
  • Development of tripeptide-cyclotriphosphazene derivatives: In vitro cytotoxicity, genotoxicity studies and molecular docking analysis within ovarian and prostate cancer cell line receptors. Kaplan, Çalışkan, Çapan, Tekin, Hassan, Qaoud MT, et al Polyhedron. 2024. https://doi.org/10.1016/j.poly.2024 - 2024
  • Effects of lesinurad on HEK-293 human kidney cells: In vitro and molecular docking evaluation. Tugce BORAN, Mahmoud ABUDAYYAK, Mohammed T. QAOUD Journal of Research in Pharmacy. 2024;28(3). http://dx.doi.org/10.29228/jrp.733 - 2024
  • Biological, phytochemical and molecular docking characteristics of Laurus nobilis L. fresh leaves essential oil from Palestine. Jaradat, Hawash, Qaoud MT et al BMC Complementary Medicine and Therapies. 2024;24. 10.1186/s12906-024-04528-9 - 2024
  • Molecular docking studies and biological evaluation of isoxazole-carboxamide derivatives as COX inhibitors and antimicrobial agents. Hawash M, Jaradat N, Abualhasan M, Qaoud MT et al 3 Biotech. 2022 Dec;12(12):342. https://doi.org/10.1007/s13205-022-03408-8 - 2023
  • Anticancer activity of thiophene carboxamide derivatives as CA-4 biomimetics: Synthesis, biological potency, 3D spheroid model, and molecular dynamics simulation. Hawash M, Qaoud MT et al Biomimetics. 2022 Dec 17;7(4):247. https://doi.org/10.3390/biomimetics7040247 - 2023
  • New thiazole carboxamide derivatives as COX inhibitors: design, synthesis, anticancer screening, in silico molecular docking, and ADME profile studies. Hawash M, Jaradat N, Sabobeh R, Abualhasan M, Qaoud MT. ACS omega. 2023 Aug 6;8(32):29512-26. https://doi.org/10.1021/acsomega.3c03256 - 2023
  • Design, synthesis, molecular docking studies and biological evaluation of thiazole carboxamide derivatives as COX inhibitors. Hawash,Jaradat,Abualhasan, Kadır Şüküroğlu, Mohammed T. Qaoud et al BMC chemistry. 2023 Mar 6;17(1):11. https://doi.org/10.1186/s13065-023-00924-3 - 2023
  • Antidiabetic, antioxidant, and anti-obesity effects of phenylthio-ethyl benzoate derivatives, and molecular docking study regarding α-amylase enzyme. Jaradat N, Khasati A, Hawi M, Hawash M, Shekfeh S, Qneibi M, Eid AM, Arar M, Qaoud MT. Scientific Reports. 2022, https://doi.org/10.1038/s41598-022 - 2022
  • Peroxisome proliferator-activated receptors as superior targets for treating diabetic disease, design strategies-review article. T QAOUD M, Almasri I, Önkol T. Turkish Journal of Pharmaceutical Sciences. 2022 Jun 27;19(3):353. https://doi.org/10.4274%2Ftjps.galenos.2021.70105 - 2022
  • The ultrashort peptide OW: a new antibiotic adjuvant. Al Tall Y, Abualhaijaa A, Qaoud MT, Alsaggar M, Masadeh M, Alzoubi KH. Current pharmaceutical biotechnology. 2019, https://doi.org/10.2174/1389201020666190618111252 - 2019
  • Antimicrobial and antibiofilm activity of UP-5, an ultrashort antimicrobial peptide designed using only arginine and biphenylalanine. Almaaytah A, Qaoud MT et al Pharmaceuticals. 2018 Jan 2;11(1):3. https://doi.org/10.3390/ph11010003 - 2018
  • Hybridization and antibiotic synergism as a tool for reducing the cytotoxicity of antimicrobial peptides. Almaaytah A, Qaoud MT, Abualhaijaa A, Al-Balas Q, Alzoubi KH. Infection and drug resistance. 2018, https://doi.org/10.2147/IDR.S166236 - 2018

Articles published in other peer reviewed international journals

  • Homology Modeling of Human Indoleamine-Pyrrole 2, 3-Dioxygenase-2 (hIDO2) and Virtual Screening Approaches to Identify Novel, Potent, and Selective HIDO2 Inhibitors. Mohammed Qaoud, Murat Şüküroğlu Palestinian Medical and Pharmaceutical Journal. 2023;8(3):11. https://doi.org/10.59049/2790-0231.125 - 2023
  • Technical insight into biodegradable polymers used in implants. Masadeh R, Qaoud M. et al Jordan Journal of Pharmaceutical Sciences. 2018 Sep 19;11(3). https://archives.ju.edu.jo/index.php/jjps/article/view/102520 - 2018
Thesis Supervision

Doctorate Thesis Supervised

  • Synthesis and Investigation the Biological Activity of New İndolamine-Pyrrole 2,3-Dioxygenase (hIDO) Inhibitors Derived from Procurer Compounds Based on Chemical Modification and Virtual Screening Method. - 2023

Master Thesis Supervised

  • The design of highly potent ultrashort conjugated antimicrobial peptides against planktonic and biofilm forming methicillin-resistant Staphylococcus aureus - 2017
Awards
  • The Turkey Buslari scholarship (2018)
  • DAAD Short-term research scholarship award in Biotechnology and Biomedicine center (BBZ), Leipzig- Germany (2017)
  • The German Academic Exchange Service (DAAD) Scholarship (2014)
Research Areas
  • I am an experienced researcher with a robust track record in the fields of drug design and ADMET development, homology modeling, and molecular docking studies. My expertise also extends to organic chemistry, where I have conducted extensive research in NMR and LCMS spectrometry analysis. Additionally, my work encompasses the exciting realm of nanotechnology, where I have been involved in innovative projects. Furthermore, I have a keen interest in antimicrobial peptide design, synthesis, analysis, and evaluation, a crucial area in today's world of evolving pathogens. My research also delves into the intricacies of toxicity assessment and MTT antiproliferative studies, contributing valuable insights to drug development and safety. With a deep passion for interdisciplinary science, my work strives to bridge the gap between molecular insights and practical applications in the pursuit of novel therapeutic solutions.